ESI 2019 Formulary Exclusions; No Diabetes Drug Changes
Express Scripts has released its Exclusion List Changes for the 2019 National Preferred commercial formulary.
Express Scripts has released its Exclusion List Changes for the 2019 National Preferred commercial formulary.
Senseonics has announced the official US launch of the Eversense CGM as well as its first commercial coverage by Horizon BCBS of New Jersey and Horizon Healthcare of New Jersey. According to the press release, product shipments began the last week of July. Tomorrow, August 8, 2018, Senseonics is holding its Q2 ’18 earnings call and will likely provide more insight into the Eversense launch.
Dexcom hosted its Q2 ’18 earnings call and provided updates to its CGM marketing and pipeline activities. Of note, Terry Gregg, former CEO and Chairman of the Board, has retired. Kevin Sayer, Dexcom’s current CEO, will fill the position. Below are highlights from the call.
FDA has approved an extended, 14-day wear time (previously 10-day) for Abbott Freestyle Libre in addition to reducing sensor warm-up time to 1 hour (previously 12 hours). In response to this expanded approval, Dexcom’s stock price dropped ~6% today. Abbott has not issued a press release yet, and the Libre US website is not yet updated. Below, FENIX provides insight into the Libre label update as it relates to the CGM market.
Roche hosted its Q2 ’18 earnings call and briefly discussed its diabetes devices portfolio including Solo micropump, which recently received CE Mark. Importantly, Roche senior management disclosed their intentions to bring the Solo micropump to the US. Below are highlights from the call including insights from Roche’s recent collaboration and investment in Care Innovations.
Roche has received CE Mark for the Accu-Chek Solo micropump. Recall, during Roche’s Q4 ’17 earnings call, the company added the Solo micropump to its European launch timeline. The device had been noticeably absent in recent years. In the coming weeks, Roche will initiate a limited pilot launch starting in Austria, Poland, Switzerland, and the UK. Below, FENIX provides insight into the Solo micropump including its potential use in a closed-loop system.
Novartis and Abbott both held their respective earnings calls today and provided updates to their respective commercial and pipeline products. Of note, Novartis disclosed it has discontinued development of LIK066 (dual SGLT1/2 inhibitor) for the treatment of obesity. Abbott believes it will be able to reach 1 million global Libre users by YE ’18. Below are highlights from the respective Q2 ’18 earnings calls.
J&J hosted its Q2 ’18 earnings call and provided brief updates on its diabetes business. Importantly, senior management did not make any comments regarding the early stopping of the CREDENCE study or the delay in the CANVAS/R CV indication. Below are highlights from the Q2 2018 J&J earnings call.
Beta Bionics has initiated (press release) their home-use clinical trial (CT.gov record)of an insulin-only iLet AP system. Additionally, Ed Damiano, Beta Bionic’s CEO, presented at the Friends For Life conference and provided an update on the iLet commercial device. Below, FENIX provides analysis of the iLet study as well as implications to the glucagon market.
A new trial (MOBILE) evaluating Dexcom’s G6 CGM vs. SMBG in 207 T2DM patients has been observed. With this trial, Dexcom appears to be moving beyond “intensive insulin-using T2DM” patients and into “basal-only,” which is a considerably larger market opportunity. Below, FENIX provides further details into the study design as well as thoughts on how Dexcom may utilize these results for expanding the G6 CGM eligible population.