ADA 2022 Key Press Releases (June 3)
On the first day of ADA 2022, four cardiometabolic-related news items were observed from Novo, Abbott, Dario, and Zealand. Below, FENIX provides context and analysis for the announcements.
On the first day of ADA 2022, four cardiometabolic-related news items were observed from Novo, Abbott, Dario, and Zealand. Below, FENIX provides context and analysis for the announcements.
Two cardiometabolic-related news items have been observed: The first trial in the cagrisema pivotal program, called “REDEFINE,” has been observed (view CT.gov record); and Lannett provided updates to its bs-glargine pivotal trial (press release). Below, FENIX provides highlights and insights for the respective new items.
Three cardiometabolic-related news items have been observed: Abbott issued a press release addressing the recent FDA clearance of its Freestyle Libre 3 (view press release); Lexicon announced it has resubmitted the sota HF NDA; and Dexcom issued a press release responding to recent media and market speculation that the company was in the process of acquiring Insulet (view press release). Below, FENIX provides highlights and insights for the respective new items.
Today, FDA updated its 510(k) website which shows that Abbott’s Libre 3 received FDA approval on Thursday, May 26, 2022. Although no Abbott press release has been observed, likely due to the US Memorial Day holiday weekend, Abbott is expected to issue a press release on Tuesday May 31 and have a full promotional booth at the upcoming ADA congress in New Orleans (June 3-7).
A series of cardiometabolic-related news items have been observed: Bigfoot announced it has appointed Matt Rainville (view LinkedIn) as CCO; Medtronic hosted its CY Q1 ’22 (FY Q4 ’22) earnings call (press release; slides); Pfizer announced FDA granted Fast Track designation to Pfizer’s ervogastat+clesacostat combination therapy for NASH; and ReShape LifeSciences and OpenLoop announced a collaboration for a nationwide launch of reshapecare. Below, FENIX provides highlights and insights for the respective new items.
Three cardiometabolic-related news items have been observed: During the ESC’s 2022 HF Congress, Bayer presented late-breaking data from an exploratory FIDELITY post hoc analysis; Lilly announced plans to invest $2.1B in new Indiana manufacturing sites; and Oramed recently announced it has been granted a US patent for its oral GLP-1RA+insulin combination therapy in T2DM. Below, FENIX provides highlights and insights for the respective new items.
Late last week, Lilly disclosed Mounjaro will be offered at $974.33 WAC across all available doses. Additionally, during Lilly’s fireside chat at UBS 2022 (view replay), Mike Mason, Lilly’s SVP and President of Diabetes briefly commented on Lilly’s pricing rationale for tirzepatide (discussed below). As a follow-up to FENIX’s Mounjaro label and website analysis (previous FENIX insight), FENIX has conducted a Mounjaro pricing analysis, including insight into why Lilly may opt to create a second brand for the tirzepatide obesity indication.
A series of cardiometabolic-related news items have been observed from Provention Bio, Lifescan, Diamyd, Dario, Nemaura, and Adocia. Below, FENIX provides highlights and insights for the respective new items.
Late last week, FDA approved Lilly’s tirzepatide, branded as Mounjaro (mown-JAHR-OH), for the treatment of adults with T2DM (view label; previous FENIX insight). Below, FENIX has conducted a label and website analysis, including potential insight into the Mounjaro launch.
Three cardiometabolic-related news items have been observed: MannKind announced plans to acquire Zealand’s V-Go insulin delivery device; Sernova and Evotec announced an exclusive global strategic partnership to develop an implantable iPSC-based beta cell replacement therapy and hosted an associated investor call (listen to webcast here); and AACE has updated its NAFLD practice guidelines which favor GLP-1RAs (view guidelines). Below, FENIX provides highlights and insights for the respective new items.