Tag Archives: Biomea Fusion

The ITCA 650 Story Lives on; i2o Therapeutics Appoints Kurt Graves as CEO; Biomea Appoints Juan Pablo Frias as CMO

Two cardiometabolic-related news items have been observed: i2o Therapeutics announced the appointment of Kurt Graves as CEO and disclosed ITCA 650 was granted an FDA adcom on September 21, 2023 (view press release); and Biomea Fusion announced the appointment of Juan Pablo Frias as CMO (view press release). Below, FENIX provides highlights and insights for the respective news items, including thoughts on why i2o may not actually be looking to commercialize the ITCA 650 drug/device combo.

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ADA 2023 Key Press Releases (June 24)

On the second day of ADA 2023, ten cardiometabolic-related news items were observed from Lilly, Zealand, BI, Novo Nordisk, Biomea Fusion, Sciwind Biosciences, Medtronic, Vertex, and Esperion. Below, FENIX provides context and analysis for the announcements.

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Viking Announces Positive Ph1 GLP-1/GIP Dual Agonist Topline Results and Initiates Oral Formulation Development; Zealand Ph1a Amylin Analog Results; Biomea Ph2 Menin Inhibitor Results

Four cardiometabolic-related news items have been observed: Viking Therapeutics announced positive topline results from the Ph1 SAD/MAD clinical trial evaluating its novel QW subcutaneous GLP-1+GIP dual agonist (VK2735; view press release) and initiated a new Ph1 study for an oral formulation of VK2735 (view press release); Zealand Pharma announced positive results from a Ph1a study of ZP8396, an amylin analog, assessing safety and PK/PD effects in healthy lean and overweight people (view CT.gov record; press release); and Biomea Fusion announced positive topline results for the first two cohorts enrolled in the Ph2 portion of its ongoing Ph1/2 COVALENT-111 study (view CT.gov record) evaluating BMF-219, a covalent menin inhibitor (view press release). Below, FENIX provides highlights and insights into the respective news items.

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