Tag Archives: ionis

JPM 2024 Day 3: TRNS, ESPR, IONS, AMRN, EMBC, and VTRS

On the third day of JPM 2024, FENIX has provided coverage of presentations by other CVRM companies, including Terns, Esperion, Ionis, Amarin, Embecta, and Viatris. Tomorrow is the final day of the JPM 2024 conference with presentations from Lexicon, Mannkind, and Xeris.

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Terns Announces Positive Topline Ph2a NASH Data; Ionis Q2 ’23 Earnings

Two cardiometabolic-related news items have been observed: Terns Pharmaceuticals announced positive topline results from its Ph2a DUET trial evaluating TERN-501 as a monotherapy or in combination with TERN-101 for the treatment of NASH (view CT.gov record; press release); and Ionis hosted its Q2 ’23 earnings call (view press release; slides). Below, FENIX provides highlights and insights into the respective news items.

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Alnylam and Regeneron Q2 ’23 Earnings; Ionis and Novartis Partner for New Lp(a) Therapy; NeuroBo Receives IRB Approval for Ph2a DA-1241 Study in NASH

Four cardiometabolic-related news items have been observed: Alnylam (press release; slides) and Regeneron (press release; slides) hosted their respective Q2 ’23 earning calls; Ionis announced it entered a collaboration and license agreement with Novartis for the discovery, development, and commercialization of a medicine for patients with Lp(a)-driven CVD (view press release); and NeuroBo Pharmaceuticals announced it received IRB approval for its first site to proceed with the Ph2a clinical trial of DA-1241 (GPR119 agonist) for the treatment of NASH (view press release). Below, FENIX provides highlights and insights for the respective news items.

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Afon to Launch Non-Invasive Blood Glucose Sensor in 2024; DEKA ACE Pump Receives 510(k) Clearance; Novo Nordisk Launches Wegovy in Germany; Ionis Completes CARDIO-TTRansform Enrollment

Four cardiometabolic-related news have been observed: Afon Technology is planning to launch a noninvasive blood glucose sensor, called Glucowear, in 2024 (view article); DEKA Research and Development received 510(k) clearance for its DEKA ACE Pump System (view 510(k) decision letter); Novo Nordisk launched Wegovy in Germany without coverage from public health insurance (view article); and Ionis announced the completion of enrollment for its Ph3 CARDIO-TTRansform CVOT of eplontersen in patients with ATTR-CM (view CT.gov record). Below, FENIX provides highlights and insights into the respective news items, including thoughts on who may be interested in commercializing the DEKA pump.

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Viking Topline Ph2b VK2809 NASH Data; Chinook and Ionis Partner to Develop ASO Therapy for CKD

Two cardiometabolic-related news items have been observed: Viking Therapeutics announced positive topline results from its Ph2b VOYAGE study evaluating VK2809, an oral thyroid beta receptor (TRβ) agonist, in patients with biopsy-confirmed NASH (F2 and F3; view CT.gov record) and hosted an associated call with investors (view press release; webcast); and Chinook Therapeutics announced it has entered into a collaboration agreement with Ionis for the discovery, development, and commercialization of an antisense oligonucleotide (ASO) therapy for a rare, severe CKD with significant unmet medical need (view press release). Below, FENIX provides highlights and insights into the respective news items.

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Ionis, Lexicon, and Amarin Q1 ’23 Earnings; AstraZeneca Collaborates with Sernova for Cell Therapies

Four cardiometabolic-related news items have been observed: Ionis (view press release; slides), Lexicon (view press release), and Amarin view press release; slides) hosted their respective Q1 ‘23 earnings calls and provided CVRM-related updates; and Sernova announced a preclinical research collaboration with AstraZeneca to evaluate the use of its Cell Pouch System with AstraZenaca’s therapeutic cells (view press release). Below, FENIX provides highlights and insights into the respective news items. 

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