Two cardiometabolic-related news items have been observed: Roche and Alnylam announced topline results from KARDIA-1, a Ph2 study of zilebesiran for the treatment of hypertension (view press release); and ITBMed initiated a Ph2 exposure-response study evaluating if treatment with siplizumab (TCD601) improves beta-cell function in adults recently diagnosed with T1DM (view CT.gov record). Below, FENIX provides highlights and insights into the respective news items.